Clinical Medicine Research

ISSN Online: 2326-9057 ISSN Print: 2326-9049

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Volume 8, Issue 6, November 2019

  • Authors: Li Shaojin, Luo Jianxian, Ji Zhisheng, Yang Yuhao, Zhang Guowei, Yang Hua, Lin Hongsheng

    Abstract: The efficacy of application of Hilus pulmonic in guiding of kyphosis correction was explored by radiographic parameters and the quality of life scores of AS kyphosis patients. A retrospective analysis was performed with patients that were diagnosed as ankylosing spondylitis with kyphosis and using the hilus pulmonic to guide kyphosis correction. A total of 16 cases, 15 males and 1 female, were enrolled. The spine-pelvic imaging parameter, the SRS-22 score and ODI dysfunction score were recorded and analyzed at pre-operation and post-operation. The post-operation spine-pelvic parameters PT, SS, GK, TLK, LL, SVA and TPA were all improved compared with preoperative parameters (P < 0.05). SRS-22 score and ODI score were significantly improved after osteotomy (P < 0.05). After using the Hilus pulmonic to guide kyphosis correction, patients with AS kyphosis can obtain good radiographic parameters and physical activity ability score, and can meet the functions of head-up, standing, sitting and lying in patients after orthopedic surgery. PT、SVA、GK and TPA have significant influences on the quality of life of patients with AS kyphosis. Correcting spine-pelvic imaging parameters is important guarantees of higher quality of life after surgery.

    Received: Oct. 16, 2019 Accepted: Oct. 25, 2019 Published: Oct. 30, 2019

    DOI: 10.11648/j.cmr.20190806.11 View: Downloads:

  • Authors: Carlos Ramirez-Velazquez, Juan Carlos Paredes-Palma, Sandra Vanesa Patzi-Vargas

    Abstract: The Natural Killer T cells (NKT) constitute a population of T lymphocytes that co-express an antigen receptor (TCR) and a marker of natural killer cells (NK1.1). We have found that after stimulation through TCR, the NKT cells secrete various cytokines that play an important role in the innate immune response and have a fundamental participation in the initial stages of the immune response to many pathogens and tumours. NKT cells belong to a group of autoreactive T cells that are generated in the thymus, which is why they have been found to play an important role in the regulation of different autoimmune diseases, such as type 1 diabetes, systemic lupus erythematosus, multiple sclerosis, and others. Also, in adulthood there is an aging of the immune system known as immunosenescence, where a decrease and alteration of the function of NKT cells has been observed, which leads to a greater oncological, viral and autoimmune diseases. It has also recently been found that these cells participate in bronchial inflammation in patients with allergic asthma as well as in rhinitis and atopic dermatitis; having these cells a clear role in the regulation of various diseases and that has not been studied as a therapeutic target.

    Received: Oct. 13, 2019 Accepted: Nov. 12, 2019 Published: Dec. 17, 2019

    DOI: 10.11648/j.cmr.20190806.12 View: Downloads:

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